Background：SEZ6L （seizure related 6 homolog-like） is a 1,024 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum. Widely expressed, SEZ6L is a candidate tumor suppressor gene and may contribute to specialized endoplasmic reticulum functions in neurons. SEZ6L contains three CUB domains and five sushi （CCP/SCR） domains, whicHuman, Mouseay be involved in protein-protein interactions and signal transduction. The gene encoding SEZ6L is located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
仕様
Synonyms：KIAA0927,OTTHUMP00000198648,OTTHUMP00000198649,Seizure 6 like protein,Seizure related 6 homolog （mouse） like,Seizure related 6 homolog likeprovided,Seizure related gene 6 （mouse） like,Seizure related gene 6 like
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human SEZ6L
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
