Background：The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm.
仕様
Synonyms：fhl2a,NR1F1,Nuclear receptor ROR-alpha,Nuclear receptor RZR-alpha,Nuclear receptor subfamily 1 group F member 1,RAR-related orphan receptor A,Retinoid-related orphan receptor-alpha,Rora,RORA,RZR-ALPHA,RZRA
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.8mg/mL
Immunogen：Synthetic peptide of human RORA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：P35398
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction
