Background：The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t（3：8） translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
仕様
Synonyms：E3 ubiquitin-protein ligase RNF139,HRCA1,RCA1,Ring finger protein 139,Translocation in renal carcinoma on chromosome 8 protein,TRC8
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human RNF139
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
