Background:This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia.
仕様
Synonyms:hZIMP10,KIAA1224,MIZ,PIAS like protein hZimp10,PIAS like protein on chromosome 10,PIAS like protein Zimp10,PIAS-like protein Zimp10,RAI 17,Retinoic acid induced 17,Retinoic acid induced protein 17,Retinoic acid-induced protein 17,TRAFIP10,Zimp10,Zinc finger containing Miz1 PIAS like protein on chromosome 10,Zinc finger MIZ domain-containing protein 1,Zinc finger MIZ-type containing 1,Zmiz1,ZMIZ1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.8mg/mL
Immunogen:Synthetic peptide of human ZMIZ1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000, IHC 1:25-1:100
Swissprot:Q9ULJ6
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction