Background：Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney. Catalyzes the oxidation of the less abundant alpha-NAD（P）H isoform toform beta-NAD（P）+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk.
仕様
Synonyms：6530404N21Rik,AI452315,AW060440,C10orf59,Chromosome 10 open reading frame 59,FLJ11218,HGNC：25641,Hypothetical protein LOC55328,MAO C,MAO-C,mMAO C,Monoamine oxidase C,Monoamine oxidase-C,Renalase,Renalase FAD dependent amine oxidase,RNLS,RNLS
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human RNLS
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q5VYX0
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Neuroscience
