Background:RBM38 (RNA-binding protein 38), also known as RNPC1 or SEB4. RBM38 is a cell cycle protein found in the cytosol and the Nucleus that exists as two alternatively spliced isoforms, 1 (RNPC1a) and 2 (RNPC1b), of 239 and 121 amino acids, respectively. Independent of p53 expression, RBM38 isoform 1 induces cell cycle arrest in G1 phase througHuman, Mouseaintaining transcript stability at the 3'-UTR of p21, a regulator of cell cycle progression at S phase. RBM38 is also an mRNA splicing factor that regulates the expression of FGFR2. RBM38 contains one RRM (RNA recognition motif) domain.
仕様
Synonyms:CLL associated antigen KW 5,CLL-associated antigen KW-5,HSRNASEB,RBM38,RBM38,RNA binding motif protein 38,RNA binding protein 38,RNA binding region (RNP1,RRM) containing 1,RNA binding region containing protein 1,RNA-binding motif protein 38,RNA-binding protein 38,RNA-binding region-containing protein 1,RNPC1,SEB4,SEB4B,SEB4D,ssDNA binding protein SEB4,ssDNA-binding protein SEB4
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human RBM38
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000, IHC 1:25-1:100
Swissprot:Q9H0Z9
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling, Developmental biology, Stem cells