Background：The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2.
仕様
Synonyms：GAP III,GAP1（IP4BP）,GAP1IP4BP,GAPIII,GTPase activating protein 1 family,GTPase activating protein III,Inositol 1 3 4 5 tetrakisphosphate binding protein,Inositol 1345 tetrakisphosphate binding protein,Ins P4 binding protein,Ins P4-binding protein,Ins（1 3 4 5）P4 binding protein,Ins（1345）P4 binding protein,MGC46517,MGC47588,Ras GTPase activating protein 3,Ras GTPase-activating protein 3,RAS p21 protein activator 3,RASA 3,RASA3,RASA3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human RASA3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
