Background：The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone.
仕様
Synonyms：CD 265,CD265,FEO,LOH18CR1,Loss of heterozygosity 18 chromosomal region 1,mRANK,ODFR,OFE,OPTB7,Osteoclast differentiation factor receptor,OSTS,Paget disease of bone 2,PDB 2,PDB2,RANK,Receptor activator of NF KB,Receptor activator of NF-KB,receptor activator of nuclear factor kappa B,TNF receptor superfamily member 11a,TNFRSF11A,TNR11,TRANCER,Tumor necrosis factor receptor superfamily member 11a NFKB activator,Tumor necrosis factor receptor superfamily member 11a activator of NFKB,Tumor necrosis factor receptor superfamily member 11A
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.7mg/mL
Immunogen：Synthetic peptide of human TNFRSF11A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q9Y6Q6
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Signal transduction
