Background：The protein encoded by this gene is a member of the protein tyrosine phosphatase （PTP） family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis.
仕様
Synonyms：Protein tyrosine phosphatase G1,Protein tyrosine phosphatase non receptor type 12,Protein-tyrosine phosphatase G1,PTN12,PTP PEST,PTP-PEST,PTPG1,Ptpn12,Tyrosine protein phosphatase non receptor type 12,Tyrosine-protein phosphatase non-receptor type 12
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：1mg/mL
Immunogen：Synthetic peptide of human PTPN12
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
