Background：This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor （WT） predisposition.
仕様
Synonyms：POU class 6 homeobox 2,POU domain class 6 transcription factor 2,Retina derived POU domain factor 1,RPF 1,RPF1,Wilms tumor suppressor locus,WT 5,WT5,WTSL
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human POU6F2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：P78424
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
