Background:The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
仕様
Synonyms:A esterase 1,A-esterase 1,Aromatic esterase 1,Arylesterase 1,Arylesterase B type,ESA,Esterase A,K 45,K-45,MVCD5,Paraoxonase 1,Paraoxonase,Paraoxonase B type,Paraoxonase,plasma,Paraoxonase1,PON 1,PON,PON1,PON1,Serum aryldiakylphosphatase,Serum aryldialkylphosphatase 1,Serum paraoxonase/arylesterase 1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human PON1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:1000-1:5000, IHC 1:50-1:200
Swissprot:P27169
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience, Signal transduction