Background:The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:Angiostatin,DKFZp779M0222,Plasmin,Plasmin heavy chain A,Plasmin light chain B,Plasminogen,PLG,PLMN
Host:Rabbit
Reactivity:Human,Rat
Applications:WB,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human PLG
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000
Swissprot:P00747
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular