Background：Peptidoglycan recognition proteins （PGRPs） are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-Ia and PGRP-I∫ are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors.
仕様
Synonyms：MGC126894,MGC126896,Peptidoglycan recognition protein 1,Peptidoglycan recognition protein,Peptidoglycan recognition protein short,PGLYRP,PGLYRP1,PGRP,PGRP S,PGRP-S,PGRP1,PHRP,short,SBBI68,TAG7,TNF superfamily,member 3 （LTB）-like （peptidoglycan recognition protein）,TNFSF 3L,TNFSF3L,UNQ639/PRO1269
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human PGLYRP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：O75594
Isotype：IgG
Research Areas：Cancer, Cell Biology, Immunology, Microbiology, Neuroscience
