Background：This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains： an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide （CNP）, which upon ligand binding exhibits greatly increased guanylyl cyclase activity.
仕様
Synonyms：AMDM,ANP-B,ANPB,ANPR-B,ANPRB,ANPRB,Atrial natriuretic peptide B type receptor,Atrial natriuretic peptide receptor 2,Atrial natriuretic peptide receptor type B,Atrionatriuretic peptide receptor B,GC-B,GCB,Guanylate cyclase B,GUC 2B,GUC2B,GUCY2B,Natriuretic peptide receptor B,Natriuretic peptide receptor B/guanylate cyclase B,NPR-B,Npr2,NPRB,NPRBi
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.9mg/mL
Immunogen：Synthetic peptide of human NPR2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：P20594
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Neuroscience, Signal transduction
