Background：The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase （complex I）. Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：CI 49,CI 49kD,CI-49kD,Complex 1,mitochondrial respiratory chain,49 KD subunit,Complex I 49kD,Complex I 49kDa subunit,Complex I-49kD,mitochondrial,NADH dehydrogenase （ubiquinone） Fe S protein 2 49kDa,NADH dehydrogenase （ubiquinone） Fe S protein 2,49kDa （NADH coenzyme Q reductase）,NADH dehydrogenase [ubiquinone] iron sulfur protein 2,mitochondrial,NADH dehydrogenase [ubiquinone] iron-sulfur protein 2,NADH ubiquinone oxidoreductase 49 kDa subunit,NADH ubiquinone oxidoreductase NDUFS2 subunit,NADH-ubiquinone oxidoreductase 49 kDa subunit,NADH：ubiquinone oxidoreductase core subunit S2,Ndufs2,NDUS2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Synthetic peptide of human NDUFS2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：O75306
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Signal transduction, Tags ＆ Cell Markers
