Background：This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：CLR19.3,FCAS2,Monarch 1,Monarch-1,NACHT,leucine rich repeat and PYD containing 12,NACHT,LRR and PYD containing protein 12,NACHT,LRR and PYD domains-containing protein 12,NAL12,NLR family,pyrin domain containing 12,NLRP12,Nucleotide-binding oligomerization domain,leucine rich repeat and pyrin domain containing 12,OTTHUMP00000067227,PAN6,PYPAF7,PYRIN containing APAF1 like protein 7,PYRIN-containing APAF1-like protein 7,Regulated by nitric oxide,RNO,RNO2
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human NLRP12
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
