Background：MIG-7 protein inhibited protein phosphatase 2A to sustain Akt/GSK-3b phosphorylation and cancer-cell migration/invasion. Cancer cells overexpressing MIG-7 exhibited increased expression of ZEB-1 and Twist in parallel with epithelial-mesenchymal transition, metastasis and cancer lethality. MIG-7 protein level positively correlated with advanced stages of human lung cancers.
仕様
Synonyms：mig 7
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.9mg/mL
Immunogen：Synthetic peptide of human MIG7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
