Background：LBP1 （Upstream-binding protein 1）, also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family （grainyhead transcription factor family）. LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells. LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region. Null expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis.
仕様
Synonyms：LBP1A,LBP1B,LBP-1B,LBP-1a
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.8mg/mL
Immunogen：Synthetic peptide of human UBP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
