Background:A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仕様
Synonyms:ELAV (embryonic lethal abnormal vision Drosophila) like 3 (Hu antigen C),ELAV like protein 3,ELAV-like protein 3,ELAV3,Elavl3,Embryonic lethal,abnormal vision,drosophila,homolog-like,Hu antigen C,Hu-antigen C,HuC,HUCL,MGC20653,Paraneoplastic cerebellar degeneration associated antigen,Paraneoplastic cerebellar degeneration-associated antigen,Paraneoplastic limbic encephalitis antigen 21,PLE21
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Synthetic peptide of human ELAVL3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:Q14576
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Neuroscience