Background：This gene is a member of the Jumonji domain 2 （JMJD2） family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：bA146B14.1,GASC 1 protein,GASC-1 protein,GASC1,Gene amplified in squamous cell carcinoma 1 protein,JHDM3C,JmjC domain containing histone demethylation protein 3C,JmjC domain-containing histone demethylation protein 3C,JMJD2C,Jumonji domain containing 2C,Jumonji domain containing protein 2C,Jumonji domain-containing protein 2C,Kdm4c,KDM4C,Lysine （K） specific demethylase 4C,Lysine demethylase 4C,Lysine-specific demethylase 4C,TDRD14C,Tudor domain containing 14C
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：1mg/mL
Immunogen：Synthetic peptide of human KDM4C
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q9H3R0
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
