Background：This gene is a member of the Jumonji domain 2 （JMJD2） family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
仕様
Synonyms：JHDM3A,JmjC domain containing histone demethylation protein 3A,JmjC domain-containing histone demethylation protein 3A,JMJD2,JMJD2A,jumonji C domain containing histone demethylase 3A,Jumonji domain containing 2,Jumonji domain containing 2A,Jumonji domain containing protein 2A,Jumonji domain-containing protein 2A,KDM4A,KDM4A,KIAA0677,Lysine （K） specific demethylase 4A,Lysine-specific demethylase 4A,TDRD14A,Tudor domain containing 14A
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Synthetic peptide of human KDM4A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：O75164
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
