Background:The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
仕様
Synonyms:4,5-trisphosphate 5-phosphatase 2,51C protein,EC 3.1.3.n1,inositol polyphosphate phosphatase like 1,Inositol polyphosphate phosphatase like protein 1,Inositol polyphosphate phosphatase-like protein 1,INPPL-1,INPPL1,OPSMD,Phosphatidylinositol 3,Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2,Protein 51C,SH2 domain containing inositol 5' phosphatase 2,SH2 domain-containing inositol 5''-phosphatase 2,SH2 domain-containing inositol phosphatase 2,SHIP-2,SHIP2,SHIP2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.8mg/mL
Immunogen:Synthetic peptide of human INPPL1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:O15357
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Immunology, Neuroscience, Signal transduction