Background：This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts.
仕様
Synonyms：SYN 2,SYN II,SYN IIa,SYN IIb,SYN2,Synapsin 2,Synapsin II isoform IIa,Synapsin II isoform IIb,Synapsin2,SynapsinII,SYNII,SYNIIa,SYNIIb
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：2mg/mL
Immunogen：Synthetic peptide of human SYN2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：1000-1：5000, IHC 1：50-1：200
Swissprot：Q92777
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
