Background：This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
仕様
Synonyms：300 kDa mannose 6 phosphate receptor,300 kDa mannose 6-phosphate receptor,Cation independent mannose 6 phosphate receptor,Cation-independent mannose-6-phosphate receptor,CD222,CD222 antigen,CI Man 6 P receptor,CI Man-6-P receptor,CI MPR,CI-M6PR,CI-MPR,CIMPR,IGF 2 receptor,IGF 2R,IGF II receptor,IGF-II receptor,IGF2 receptor,Igf2r,Insulin like growth factor 2 receptor,Insulin like growth factor II receptor,Insulin-like growth factor 2 receptor,Insulin-like growth factor II receptor,M6P R,M6P/IGF2 receptor,M6P/IGF2R,M6PR,mannose 6 phosphate receptor,mannose 6 phosphate receptor,cation independent,MPR 300,MPR300,MPRI,MPRI
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human IGF2R
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：P11717
Isotype：IgG
Research Areas：Cancer, Immunology, Signal transduction, Tags ＆ Cell Markers
