Background:This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
仕様
Synonyms:DKFZp779H1622,Histidine proline rich glycoprotein,Histidine rich glycoprotein,HPRG,HRGP,Thrombophilia due to elevated HRG
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:1.4mg/mL
Immunogen:Synthetic peptide of human HRG
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3