Background：This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins （hnRNPs）. The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA （hnRNA）. These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仕様
Synonyms：Heterogeneous nuclear ribonucleoprotein F,hnRNP F,HnRNP F protein,Hnrnpf,HNRPF,HNRPF,mcs94 1,MGC110997,N-terminally processed,Nucleolin like protein,Nucleolin like protein mcs94 1,Nucleolin-like protein mcs94-1,OK/SW-cl.23,OTTHUMP00000019482,OTTHUMP00000043413,OTTHUMP00000043414,Ribonucleoprotein F
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human HNRNPF
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：P52597
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
