Background：The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 （mitochondrial）,3 hydroxy 3 methylglutaryl Coenzyme A synthase 2,3 hydroxy 3 methylglutaryl coenzyme A synthase,3-hydroxy-3-methylglutaryl coenzyme A synthase,HMCS2,HMG CoA synthase,HMG-CoA synthase,HMGCS 2,HMGCS2,Hydroxymethylglutaryl CoA synthase,Hydroxymethylglutaryl CoA synthase mitochondrial,Hydroxymethylglutaryl-CoA synthase,mitochondrial
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human HMGCS2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：P54868
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
