Background：Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 （Zinc finger protein 395）, also known as PBF （Papillomavirus-binding factor） and HDBP2 （Huntington disease gene regulatory region-binding protein 2）, is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3'-CCGG-5' sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease （HD） gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.
仕様
Synonyms：DKFZp434K1210,HD gene regulatory region binding protein 2,HD gene regulatory region-binding protein 2,HD-regulating factor 2,HDBP-2,HDBP2,HDRF-2,Huntington disease gene regulatory region-binding protein 2,Huntington's disease gene regulatory region binding protein 2,Papillomavirus regulatory factor 1,papillomavirus regulatory factor PRF 1,Papillomavirus-binding factor,PBF,PRF-1,PRF1,PTTG1IP,Si-1-8-14,Zinc finger protein 395,ZN395,znf395
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.8mg/mL
Immunogen：Synthetic peptide of human ZNF395
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q9H8N7
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Microbiology
