Background：This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：DKFZp434B027,DKFZp434J1815,F box only protein 31,F box protein 31,F-box only protein 31,FBX14,FBX31,FBX31,FBXO14,Fbxo31,FLJ22477,MGC15419,MGC9527,pp2386,Putative breast cancer tumor suppressor,SCF ubiquitin ligase specificity factor
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human FBXO31
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
