Background：This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor （EGF）-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.
仕様
Synonyms：Cadherin family member 7,Cadherin family member 7 precursor,Cadherin ME5,Cadherin related tumor suppressor,Cadherin related tumor suppressor homolog,Cadherin related tumor suppressor homolog precursor,Cadherin related tumor suppressor homolog precursor （FAT protein homolog）,Cadherin-related tumor suppressor homolog,CDHF 7,CDHF7,FAT 1,FAT tumor suppressor 1,FAT tumor suppressor homolog 1,FAT1,FAT1,hFat 1,hFAT,hFat1,Homolog of Drosophila FAT protein,Homolog of Drosophila FAT protein precursor,Homolog of Drosophila tumor suppressor FAT precursor,ME 5,ME5,nuclear form,Protein fat homolog,Protocadherin Fat 1
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human FAT1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q14517
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction
