Background:This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
仕様
Synonyms:5'-Tyr-DNA phosphodiesterase,5'-tyrosyl-DNA phosphodiesterase,AD 022,AD022,dJ30M3.3,EAP 2,EAP II,EAP2,EAPII,ETS 1 associated protein 2,ETS 1 associated protein II,ETS1 associated protein 2,ETS1-associated protein 2,ETS1-associated protein II,MGC111021,MGC9099,RP1-30M3.3,tdp2,TRAF and TNF receptor associated protein,TRAF and TNF receptor-associated protein,TTRAP,TYDP2,Tyr DNA phosphodiesterase 2,Tyr-DNA phosphodiesterase 2,Tyrosyl DNA phosphodiesterase 2,Tyrosyl-DNA phosphodiesterase 2
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human TDP2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:O95551
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling