Background:This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance.
仕様
Synonyms:E ras,E-Ras,ecat5,Embryonic stem cell expressed Ras,Embryonic stem cell-expressed Ras,Eras,ES cell expressed Ras,GTPase ERas,Ha-Ras2,HRAS2,HRASP,MGC126691,MGC126693,OTTHUMP00000065857,RASE,Small GTPase protein E Ras,v Ha ras Harvey rat sarcoma viral oncogene homolog pseudogene,v Ha ras Harvey rat sarcoma viral oncogene homolog 2
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.9mg/mL
Immunogen:Synthetic peptide of human ERAS
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:50-1:200
Swissprot:Q7Z444
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Signal transduction, Stem cells