Background:This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:DCR,DCR1,Dicer 1 ribonuclease III,Dicer 1 ribonuclease type III,Dicer,DICER,DICER1,Double-strand-specific ribonuclease,Endoribonuclease Dicer,Helicase MOI,Helicase with RNase motif,HERNA,KIAA0928,MNG1,RMSE2
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.9mg/mL
Immunogen:Synthetic peptide of human DICER1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:Q9UPY3
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling