Background：DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp （DEAD）, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：DDX 4,Ddx4,DDX4,DEAD （Asp Glu Ala Asp） box polypeptide 4,DEAD box protein 4,DEAD/H （Asp-Glu-Ala-Asp/His） box polypeptide 4,MVH,Probable ATP dependent RNA helicase DDX4,Probable ATP-dependent RNA helicase DDX4,VASA,Vasa homolog
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：1.2mg/mL
Immunogen：Synthetic peptide of human DDX4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q9NQI0
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Stem cells
