Background：CrkRS （Cdc2-related kinase, arginine/serine-rich, also designated CRK7 and CRKR） is an ubiquitous protein that appears to localize to the nucleus and link transcription and splicing machinery. CrkRS belongs to the serine/threonine protein kinase family and Cdc2/Cdkx subfamily. CrkRS has extensive proline-rich regions that resemble SH3 and WW domain binding sites, and an RS domain that is characteristic of splicing factors. The protein kinase domain of CrkRS is 89％ identical to the CHED protein kinase, also designated CDC2L5 and cell division cycle 2-like 5 （cholinesterase-related cell division controller）, however outside the kinase domains the two proteins are unique. Cell cycle control kinases can phosphorylate proteins important for differentiation and apoptosis and provide connections between proliferation, differentiation, apoptosis, and neurocytoskeleton dynamics.
仕様
Synonyms：arginine/serine-rich,Cdc2 related kinase arginine/serine rich,CDC2 related protein kinase 7,Cdc2-related kinase,CDC2-related protein kinase 7,Cdk12,CDK12,Cell division cycle 2 related protein kinase 7,Cell division cycle 2-related protein kinase 7,Cell division protein kinase 12,CRK7,CRKR,CrkRS,Cyclin-dependent kinase 12,EC 2.7.11.22,hCDK12,kiaa0904,Pksc
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human CDK12
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
