Background：The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仕様
Synonyms：AGAP-2,Agap2,Agap2 ArfGAP with GTPase domain,ankyrin repeat and PH domain 2,AGAP2,ANK repeat and PH domains 2,Arf GAP with GTP binding protein like,Arf GAP with GTP-binding protein-like,ANK repeat and PH domains 2,Arf GAP with GTP-binding protein-like,ankyrin repeat and pleckstrin homology domains 2,Arf-GAP with GTPase,ANK repeat and PH domain-containing protein 2,ArfGAP with GTPase domain,ankyrin repeat and PH domain 2,centaurin gamma1,Centaurin-gamma-1,Centg1,cnt g1,Cnt-g1,Cnt2,FLJ16430,GGAP2,GTP binding and GTPase activating protein 2,GTP-binding and GTPase activating protein 2,GTP-binding and GTPase-activating protein 2,KIAA0167,mKIAA0167,Nuclear GTPase PIKE,Phosphatidylinositol 3-kinase enhancer,Phosphoinositide 3 kinase enhancer,PI3K ENHANCER,PIKE
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human AGAP2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：Q99490
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Signal transduction
