Background：The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
仕様
Synonyms：AGP/EBP,C EBP beta,C/EBP beta,C/EBP related protein 2,CCAAT Enhancer Binding Protein beta,CCAAT/enhancer-binding protein beta,CEBPB,CEBPB,CRP2,IL 6DBP,IL6DBP,Interleukin 6 dependent binding protein,LAP,Liver activator protein,Liver enriched transcriptional activator,NF IL6,NFIL6,Nuclear factor NF IL6,Nuclear factor NF-IL6,SF B,SFB,Silencer factor B,TCF-5,TCF5,Transcription factor 5
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.8mg/mL
Immunogen：Synthetic peptide of human CEBPB
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P17676
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling
