Background:This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
仕様
Synonyms:BN 1,BN1,C C chemokine receptor type 6,C C CKR 6,C-C chemokine receptor type 6,C-C CKR-6,CC chemokine receptor type 6,CC CKR 6,CC R6,CC-CKR-6,CCCKR6,CCR 6,CCR-6,Ccr6,CCR6,CD 196,CD196,CD196 antigen,Chemokine (C C motif) receptor 6,Chemokine (C C) receptor 6,Chemokine (CC motif) receptor 6,Chemokine (CC) receptor 6,Chemokine receptor 6,Chemokine receptor like 3,Chemokine receptor-like 3,CKR 6,CKR L3,CKR-L3,CKR6,CKRL3,CMKBR 6,CMKBR6,DCR 2,DCR2,DRY 6,DRY6,G protein coupled receptor 29,G-protein coupled receptor 29,GPR 29,GPR CY4,GPR-CY4,GPR29,GPRCY 4,GPRCY4,LARC receptor,Seven transmembrane receptor lymphocyte 22,STRL 22,STRL22
Host:Rabbit
Reactivity:Human
Applications:WB,IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Synthetic peptide of human CCR6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:1000-1:5000, IHC 1:50-1:200
Swissprot:P51684
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Immunology, Signal transduction