Background：Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：alpha-1 polypeptide,CAC1D,CACH3,CACN4,CACNA 1D,Cacna1d,CACNL1A2,Calcium channel,Calcium channel L type alpha 1 polypeptide isoform 2,Calcium channel neuroendocrine/brain type alpha 1 subunit,Calcium channel voltage dependent L type alpha 1,Calcium channel voltage dependent L type alpha 1D subunit,Cav1.3,CCHL1A2,isoform 2,L type,PASNA,SANDD,Voltage dependent L type calcium channel subunit alpha 1D,Voltage gated calcium channel alpha 1 subunit,Voltage gated calcium channel alpha subunit Cav1.3,Voltage gated calcium channel subunit alpha Cav1.3,Voltage-dependent L-type calcium channel subunit alpha-1D,Voltage-gated calcium channel subunit alpha Cav1.3
Host：Rabbit
Reactivity：Human,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human CACNA1D
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：Q01668
Isotype：IgG
Research Areas：Cancer, Metabolism, Neuroscience, Signal transduction
