Background：Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis.Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.
仕様
Synonyms：Biorientation defective 1,Biorientation defective protein 1,biorientation of chromosomes in cell division 1,Biorientation of chromosomes in cell division protein 1,BOD1,BOD1,FAM44B,family with sequence similarity 44,member B,Protein FAM44B
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human BOD1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：Q96IK1
Isotype：IgG
Research Areas：Cell Biology, Epigenetics and Nuclear Signaling
