Background:The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
仕様
Synonyms:BMP-6,Bmp6,BMP6,Bone morphogenetic protein 6,Bone Morphogenic Protein 6,Decapentaplegic vegetal related,DVR6,HGNC:12686,TGFB related vegetal related growth factor,Transforming growth factor beta,Vegetal related (TGFB related) cytokine,Vegetal related growth factor (TGFB related),Vg related sequence,VG-1-R,VG-1-related protein,Vg1 related sequence,VGR,VGR-1,VGR1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:1mg/mL
Immunogen:Synthetic peptide of human BMP6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:50-1:200
Swissprot:P22004
Isotype:IgG
Research Areas:Cancer, Cell Biology, Signal transduction, Stem cells