Background：The protein encoded by this gene is part of the anion exchanger （AE） family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions.
仕様
Synonyms：AE 1,AE1,Anion exchange protein 1,Anion exchanger 1,B3AT,Band 3 anion transport protein,BND3,CD233,DI,Diego blood group,EMPB3,EPB3,Erythrocyte membrane protein band 3,Erythroid anion exchange protein,FR,Froese blood group,RTA1A,SLC4A1,Solute carrier family 4 anion exchanger member 1,Solute carrier family 4 member 1,SW,Swann blood group,Waldner blood group,WD,WD1,WR,Wright blood group
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human SLC4A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
