Background:The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
仕様
Synonyms:ADFP,Adipophilin,Adipose differentiation related protein,Adipose differentiation-related protein,ADRP,MGC10598,Perilipin-2,PLIN2,PLIN2
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Synthetic peptide of human PLIN2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:25-1:100
Swissprot:Q99541
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction