Background：This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing （NLRP） protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain （NAD）, and a C-terminal leucine-rich repeat （LRR） region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：CLR19.4,FLJ94610,HYDM,MGC126470,MGC126471,NACHT,leucine rich repeat and PYD containing 7,NACHT,LRR and PYD containing protein 7,NACHT,LRR and PYD domains containing protein 7,NACHT,LRR and PYD domains-containing protein 7,NALP7,NALP7,NLR family,pyrin domain containing 7,NLRP7,NOD12,Nucleotide-binding oligomerization domain protein 12,Nucleotide-binding oligomerization domain,leucine rich repeat and pyrin domain containing 7,PAN7,PYPAF3,PYRIN-containing APAF1-like protein 3
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human NLRP7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
