Background：Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
仕様
Synonyms：Alpha synuclein,Alpha-synuclein,Alpha-synuclein,isoform NACP140,alphaSYN,MGC105443,MGC110988,MGC127560,MGC64356,NACP,Non A beta component of AD amyloid,Non A4 component of amyloid,Non A4 component of amyloid precursor,Non-A beta component of AD amyloid,Non-A-beta component of alzheimers disease amyloid,precursor of,Non-A4 component of amyloid precursor,Non-A4 component of amyloid,precursor of,OTTHUMP00000218549,OTTHUMP00000218551,OTTHUMP00000218552,OTTHUMP00000218553,OTTHUMP00000218554,PARK 1,PARK 4,PARK1,PARK4,Parkinson disease （autosomal dominant,Lewy body） 4,Parkinson disease familial 1,SNCA,Snca synuclein,alpha （non A4 component of amyloid precursor）,SYN,Synuclein alpha,Synuclein alpha 140,Synuclein,alpha （non A4 component of amyloid precursor）,SYUA
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.1mg/mL
Immunogen：Synthetic peptide of human SNCA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
