Background：The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' （Mad） and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins （BMPs）, which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation.
仕様
Synonyms：BSP-1,BSP1,HsMAD1,JV4-1,JV41,MAD homolog 1,MAD mothers against decapentaplegic homolog 1,Mad related protein 1,Mad-related protein 1,MADH1,MADR1,Mothers against decapentaplegic homolog 1,Mothers against DPP homolog 1,SMA- AND MAD-RELATED PROTEIN 1,SMAD 1,SMAD family member 1,SMAD mothers against DPP homolog 1,Smad1,SMAD1,TGF beta signaling protein 1,Transforming growth factor-beta-signaling protein 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human SMAD1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：Q15797
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
