Background：Proteins of the matrix metalloproteinase （MMP） family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.
仕様
Synonyms：72 kDa gelatinase,72kD type IV collagenase,CLG 4,CLG 4A,CLG4,CLG4A,Collagenase Type 4 alpha,Collagenase type IV A,Gelatinase A,Gelatinase alpha,Gelatinase neutrophil,Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase,Matrix metalloproteinase 2 （gelatinase A,72kDa gelatinase,72kDa type IV collagenase）,Matrix Metalloproteinase 2,Matrix metalloproteinase II,Matrix metalloproteinase-2,MMP 2,MMP II,MMP-2,MMP2,MMP2,MONA,Neutrophil gelatinase,PEX,TBE 1,TBE-1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Synthetic peptide of human MMP2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P08253
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism
