Background：This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：ASPN,ASPN protein,ASPN,Asporin （LRR class 1）,Asporin,Asporin proteoglycan,FLJ20129,LRR class 1,Periodontal ligament associated protein 1,Periodontal ligament-associated protein 1,PLAP 1,PLAP-1,PLAP1,SLRR 1C,SLRR1C,Small leucine rich protein 1C
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human ASPN
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
