Background:DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
仕様
Synonyms:Ddx58,DDX58,DEAD (Asp Glu Ala Asp) box polypeptide 58,DEAD (Asp Glu Ala Asp/His) box polypeptide,DEAD box protein 58,DEAD/H (Asp Glu Ala Asp/His) box polypeptide RIG1,DKFZp434J1111,DKFZp686N19181,FLJ13599,Probable ATP dependent RNA helicase DDX58,Probable ATP-dependent RNA helicase DDX58,Retinoic acid inducible gene 1 protein,Retinoic acid-inducible gene 1 protein,Retinoic acid-inducible gene I protein,RIG I,Rig-1,RIG-I,RIG1,rigi,RLR 1,RNA helicase,RNA helicase RIG I,SGMRT2
Host:Rabbit
Reactivity:Human
Applications:WB,IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Synthetic peptide of human DDX58
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000, IHC 1:100-1:300
Swissprot:O95786
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Immunology