Background:The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif whicHuman, Mouseay be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
仕様
Synonyms:Brd4,BRD4-NUT FUSION,BRD4-NUT fusion oncoprotein,BRD4,Bromodomain containing 4,bromodomain containing protein 4,Bromodomain-containing protein 4,CAP,chromosome associated protein,HUNK1,HUNKI,MCAP,Mitotic chromosome-associated protein,Protein HUNK1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Synthetic peptide of human BRD4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000
Swissprot:O60885
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling